Tidal volume inspiratory reserve volume12/30/2023 ![]() In very early stage of pregnancy, the corpus luteum secretes 17- hydroxyl progesterone. There are number of changes in the anatomical, physiological and biochemical parameters during pregnancy, which begin immediately following conception and continue for entire pregnancy. Conclusion: The changes in pulmonary function are attributed to major adaptations in the maternal respiratory system and are influenced by the mechanical pressure of enlarging gravid uterus, elevating the diaphragm and restricting the movements of lungs thus hampering the forceful expiration and also might be due to decline in alveolar Pco 2 caused by hyperventilation which acts as bronchoconstrictor in addition to sensitization of respiratory center due to progesterone There was significant decrease in Inspiratory Reserve Volume and Inspiratory Capacity. There was a gradual decrease in tidal volume in 1 st, 2 nd and 3 rd trimesters of pregnancy when compared to non pregnant women. Results: There was gradual significant increase in respiratory rate in all trimesters of pregnancy. Respiratory parameters in control and study groups were recorded. The subjects were distributed in four groups, as control (non-pregnant) group and 1 st, 2 nd and 3 rd trimester pregnant groups. Materials and Methods: A cross-sectional study was carried in 200 healthy women in the age range of 19-35 years. Aims: The aim of the study was designed to evaluate the pulmonary function tests in 1 st, 2 nd and 3 rd trimesters of pregnancy and compare them with non-pregnant control group. However there is insufficient information regarding the changes in respiratory parameters in different trimesters of pregnancy. Many of these changes begin soon after fertilization and continue throughout the gestation and changes in the respiratory system are part of the same process. Bagaliīackground: The anatomical, physiological and biochemical adaptations in pregnancy are profound.
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